While NAD+ itself is the molecule your cells need, it’s rarely supplemented directly because it has trouble reaching your cells intact – imagine trying to deliver a delicate package that falls apart before reaching its destination. Instead, we use various precursor molecules that your body can efficiently transform into NAD+.

NAD precursors work best when taken consistently every day. It’s similar to keeping a car’s gas tank from running too low – regular intake helps maintain stable NAD levels in your cells.

Morning vs evening: Most people prefer taking NAD boosters in the morning since they can promote energy production. If you experience any energizing effects, an early dose helps prevent sleep disruption. If you don’t notice any stimulating effects, you can take it any time that fits your schedule.

Here are a few NAD Boosters.

• Glutatonic: Carried at Pelage Medi Spa Glutathione is a substance made from the amino acids glycine, cysteine, and glutamic acid. It is produced by the liver and involved in many body processes. Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function. Niacin, (also known as vitamin B3 The basic building block for NAD function) is a vital nutrient your body needs to function properly. It plays a role in various bodily processes, including converting food into energy, supporting metabolism, and maintaining the health of the nervous system, digestive system, and skin. Inositol, often referred to as vitamin B8 (though technically not a true vitamin as the body can synthesize it), is a type of sugar molecule naturally occurring in the human body and found in various foods. It plays a crucial role in cellular structure, messaging within cells, and influencing the action of insulin and neurotransmitters like serotonin and dopamine. 

• NR (Nicotinamide Riboside): As one of the most well-studied NAD boosters, NR has earned its reputation through extensive clinical research¹. Your body efficiently processes this molecule through a well-mapped conversion pathway, making it a reliable choice for those seeking evidence-based NAD supplementation. Think of NR as having a special “fast pass” through your cellular machinery – it encounters fewer biological obstacles on its journey to becoming NAD.
• NMN (Nicotinamide Mononucleotide): Available as pure NMN powder, this molecule is slightly larger than NR but still effectively raises NAD levels in your body. The cellular uptake mechanism of NMN is complex, potentially requiring conversion to NR before entering cells or utilizing a specific transporter protein.² Once inside the cell, NMN is one step closer to NAD+ in the conversion pathway.

 These comprehensive formulations combine multiple NAD precursors, typically including both NMN and NR, to potentially optimize NAD production through various pathways. Think of it as taking multiple routes to the same destination – while one precursor might be more effective in certain tissues, another could work better elsewhere, potentially providing more complete coverage for your NAD-boosting goals.

Individual Response and Monitoring: It’s essential to remember that everyone responds differently to NAD+ therapy. Regular monitoring of your response, both through physical symptoms and lab testing (if recommended by your provider), is crucial for adjusting the injection frequency as needed.